Unlocking Rational Design of Induced Proximity Drugs Through AI-Powered Structural Proteomics
12:00 pm - Thursday 14th January 2027
- Demonstrating how structural proteomics and AI can reveal the architecture and dynamics of induced proximity complexes that traditional structural approaches cannot capture
- Establishing a rational design framework for molecular glues and targeted protein degraders to improve potency, selectivity, and developability
- Showcasing how AI-guided structural insights accelerated Protai’s oncology pipeline, from protein complex modelling through in vivo efficacy and IND-enabling development