Felix Metzner
Structural Researcher Boehringer Ingelheim
Seminars
Thursday 14th January 2027
Structural Insights into Ligand Recognition and Modulation of a Class A GPCR
2:00 pm
- Cryo-EM captures chemically diverse ligands bound to active and inactive states of a class A GPCR
- Comparisons across functional states reveal molecular determinants of receptor activation and inhibition
- Integrated structural and functional data guide rational ligand design